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Neurite outgrowth in cocultures of neurons and astrocytes. The length of the longest neurite (A), total neurite lengths (B), and number of neurites per neuron (C) were analyzed in hippocampal neuons seeded on top of astrocytes that had or had not been treated with LPS or antibody against CHL1. Data represent mean ± SEM values for n > 200 neurons from 2 independent experiments. *P<0.05 versus control group without LPS; #P<0.05 versus LPS alone group.
