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Analysis of raloxifene reaction with HLM-bioreactors in the presence of GSH, 5 min. incubation: (a) SRM chromatogram of raloxifene-glucuronides with mass transition m/z 650 to 474, in which peak 1 and 2 represent 6-R-G and 4-R-G, respectively. (b) CID chromatogram of parent ion m/z 650. (c) SRM chromatogram of raloxifene-glutathione conjugate with mass transition m/z 779 to 650. (d) Product ion chromatogram of parent ion m/z 779.
