Table 3.
Arm | A | p | B | p | C | p | D | p | ||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Median PFS, months | 5.9 | 4.2 | 2.2 | 3.5 | ||||||||
Predicated 6-month PFS rate*, % | 16 | 0.002 | 17 | 0.03 | 15 | NS | 16 | NS | ||||
6-month PFS rate, % | 50 | 40 | 11 | 23 | ||||||||
95% | 33–66 | 25–57 | 4–26 | 14–40 | ||||||||
Median OS months | 10.5 | 10.5 | 5 | 8 | ||||||||
Predicted 1 yr OS rate*, % | 34 | NS | 35 | NS | 18 | NS | 21 | <0.1 | ||||
Observed 1 year OS rate, % | 34 | 48 | 14 | 33 | ||||||||
95%Cl | 21–47 | 30–60 | 6–30 | 22–47 | ||||||||
Number of patients evaluated | 35 | 38 | 35 | 51 |
Calculated from Korm et.al.25