Table 3.
Distribution of hippocampal tangle ratings as a function of dementia severity in schizophrenia patients
CDR < 2 (N =46) | CDR > 2 (N =52) | |
---|---|---|
Hippocampal tangle rating | ||
Absent | 21 (37.5%) | 11 (21.2%) |
Sparse | 25 (44.6%) | 19 (36.5%) |
Moderate | 2 (3.6%) | 5 (9.6%) |
Severe | 8 (14.3%) | 17 (32.7%) |
Note: Number of subjects within each tangle rating category (percentages of column total in parentheses). For hippocampal neurofibrillary tangles, nonparametric analyses revealed a main effect for dementia severity (χ2 = 7.73, df = 3, p < .05). There was no effect of ApoE4 carrier status (p = .17).