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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Hum Immunol. 2010 Jan;71(1):14–22. doi: 10.1016/j.humimm.2009.08.012

Fig. 2.

Fig. 2

Host encoded HLA-A*0201 peptides that are unique or increased following influenza A virus infection. Comparative mass spectrometric analysis of class I HLA-A*0201 peptides purified from naïve and influenza infected HeLa cells identified host-encoded peptides with unique or increased presentation following influenza infection. A Venn diagram reveals overlap in the presentation of unique and increased peptides observed between the PR8 (blue), 7485 (red), and 309 (green) influenza strains. The twenty host peptides unique to influenza infection were presented on a strain-by strain basis (PR8-5, 7485-14, and 309-1). While the majority of peptides with upregulated presentation following influenza infection were limited to the infecting strain, 39 host encoded HLA-A*0201 peptides had increased presentation during infection with both H1N1 strains (PR8 and 7485), 6 peptides were upregulated following 7485 and 309 infection, and 5 peptides exhibited increased presentation during infection with all influenza A virus three strains.