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. Author manuscript; available in PMC: 2011 Jan 15.
Published in final edited form as: Gene. 2010 Jan 15;450(1-2):8–17. doi: 10.1016/j.gene.2009.09.007

Figure 2. Schematic representation of histone demethylase families.

Figure 2

Dmel\JHMD1, Dmel\JHMD2 and Dmel\Kdm4A are each highly conserved with their human homolog counterparts. Shown is a schematic representation (drawn to scale) of the conserved domains and their location within each of the JHMD1, JHMD2 and Dmel\Kdm4A family members. Structural domains and locations were obtained at CDD/NCBI. Numbers represent percentage identity and similarity with respect to the corresponding Drosophila homolog. The positions of the JumonjiC (JmjC) and JumonjiN (JmjN) domains are indicated. Zinc-like finger, CXXC-zinc finger, PHD and tudor domains and their locations are also shown.