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. Author manuscript; available in PMC: 2010 Jun 1.
Published in final edited form as: Gene Ther. 2009 Dec;16(12):1416–1428. doi: 10.1038/gt.2009.101

Table 1.

Structure-function analysis of clade E vector subset.

Isolate Clade Species of Isolation Δhu.37 No. of Singleton Yield (× 103 GC/cell) Gene Transfer (μg hAAT/ml)
hu.37 E Human 0 0 50 57
hu.41 E Human 3 2 33 1.4
rh.40 E Rhesus 4 1 1 n/a
AAV8 E Rhesus 48 0 80 72

Δhu.37 identifies the number of residues different from hu.37. Yields represent numbers of GC produced per HEK293 cell following transfection. Gene transfer is measured following intraportal administration of 1 × 1011 GC AAV.CB.hAAT particles to NCR nude mice in the serum at peak expression.