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. Author manuscript; available in PMC: 2010 Dec 22.
Published in final edited form as: Biochemistry. 2009 Dec 22;48(50):12024–12033. doi: 10.1021/bi9013352

Figure 8.

Figure 8

Correlation relevance summed over chains (cREL) for all three simulations. a) cREL vs residue number. Residue identities are labeled at peak values. Bottom bars indicate residues with high conservation across species, or with either nickel or DNA binding function as labeled. Light and dark grey regions represent the DBD and MBD respectively. b) Correlation relevance summed over chains (cREL) for the HT simulation applied to a color scheme (red is the highest, blue is the lowest) on a single chain the initial structure of the HT form of NikR. The rest of the protein is present but deemphasized and uses the same color scheme as Figure 1. The figure suggests strong influence on the rest of the protein by the secondary structure segments involved in both DNA and nickel binding.