Figure 3.
The geometries optimized at the QM/MM(B3LYP/6-31G*:AMBER) level for the nucleophilic attack step. The key distances in the figure are in Å. Carbon, oxygen, nitrogen, phosphorous, and hydrogen atoms are colored in green, red, blue, orange, and white, respectively. The QM atoms are represented as ball and stick, and the surrounding residues rendered with stick. All non-polar hydrogen atoms are not shown for clarity.