Average pupillary light responses to three different monochromatic light stimuli, 450 nm (blue trace), 530 nm (green trace), and 610 nm (red trace) necessary to produce approximately a half-maximal pupillary constriction at (A) 1 second, (B) 3.16 seconds, (C) 10 seconds, (D) 31.6 seconds, and (E) 100 seconds (n=6). The black bar in the upper right hand corner of each panel indicates the measurement interval utilized in each of the five duration conditions. Note the increase in the disparity of the initial response to each of the three wavelengths as stimulus duration is increased.