Table 1.
Transplantable and spontaneous metastasis of SOSP-9607 variants
| SOSP 9607 variants | Time to autopsy after tumor injection (weeks) | Tumor take rate at inoculation site (mice with tumors/mice inoculated) | Mice with macroscopically visible tumors | Mice with microscopically visible tumors |
|---|---|---|---|---|
| D5 | 6 | 1/5 | 0/5 | 0/5 |
| D6 | 6 | 1/5 | 0/5 | 0/5 |
| E4 | 6 | 1/5 | 0/5 | 0/5 |
| E7 | 6 | 1/5 | 0/5 | 0/5 |
| F4 | 6 | 4/5 | 1/5 | 1/5 |
| F5 | 6 | 5/5 | 4/5 | 5/5 |
| F7 | 6 | 5/5 | 2/5 | 2/5 |
| F9 | 6 | 5/5 | 1/5 | 3/5 |
| G6 | 6 | 5/5 | 0/5 | 3/5 |
| G9 | 6 | 5/5 | 0/5 | 2/5 |
| H1 | 6 | 1/5 | 0/5 | 0/5 |
| H7 | 6 | 1/5 | 0/5 | 0/5 |
| 9607 | 6 | 2/5 | 2/5 | 2/5 |