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. 2009 Oct 20;158(6):1477–1485. doi: 10.1111/j.1476-5381.2009.00406.x

Figure 2.

Figure 2

Effect of the putative 5-hydroxytryptamine (5-HT)2C receptor agonist RO-60-0175 on 5-HT cell firing. (A) Spike train (upper trace) and rate-meter recording of the inhibitory effect of RO-60-0175 on the firing of a single 5-HT neurone, and reversal by SB 242084. Doses in mg·kg−1. (B) Group data of the effect of RO-60-0175 followed by SB 242084. Data are mean + standard error of the mean values, n= 6 cells. *P < 0.01 versus pre-drug values. #P < 0.01 versus WAY 161503 (1.0 mg·kg−1 i.v.; one-way analysis of variance with least significant difference post hoc test).