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. 2009 Oct 20;158(6):1477–1485. doi: 10.1111/j.1476-5381.2009.00406.x

Figure 4.

Figure 4

Effect of the 5-hydroxytryptamine (5-HT) agonist lysergic acid diethylamide (LSD) on 5-HT cell firing. (A) Spike train (upper trace) and rate-meter recording of the inhibitory effect of LSD on the firing of a single 5-HT neurone. The inhibition was not affected by SB 242084 or ritanserin, but reversed by WAY 100635. Doses in mg·kg−1 except LSD (µg·kg−1). (B) Group data of the effect of LSD. Data are mean + standard error of the mean values, n= 6 cells. *P < 0.05, **P < 0.01, ***P < 0.001 versus pre-drug values. #P < 0.001 versus LSD (10 µg·kg−1 i.v.; one-way analysis of variance with least significant difference post hoc test).