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. 2009 Oct 8;158(6):1513–1526. doi: 10.1111/j.1476-5381.2009.00425.x

Figure 7.

Figure 7

The effect of P2X7 receptor ligands on [3H]-GSK1271360 binding to membranes prepared from HEK293 cells stably expressing the dog P2X7 receptor. The radioligand concentration was 2 nM, and specific binding was defined with 10 µM compound-17. The data are the mean ± SEM of three separate experiments. BBG, brilliant blue G; compound-17, N-[2-({2-[(2-hydroxyethyl)amino]ethyl}amino)-5-quinolinyl]-2-tricyclo[3.3.1.13,7]dec-1-ylacetamide; GSK1271360, 2-(1-adamantyl)-N-[2-({2-[bis(2 hydroxyethyl)amino]ethyl}amino)quinolin-5-yl]acetamide; KN62, 1-(N,O-bis-[5-isoquinoline-sulphonyl]-N-methyl-L-tyroyl)-4-phenyl-piperazine.