Table 1.

Inhibition of platelet aggregation by flavonoids (IC₅₀± SEM in µM)

	Apigenin	Genistein	Quercetin	Rutin
Thrombin 0.2 U·mL−1	56.4 ± 9.8	>100	37.2 ± 5.8	>100
PAR1-AP 25 µM	54.4 ± 5.7	56.0 ± 5.5	22.0 ± 4.2	>100
PAR4-AP 150 µM	20.8 ± 3.5	47.6 ± 6.5	23.1 ± 1.5	>100

Washed platelets were stimulated with thrombin, PAR₁-AP or PAR₄-AP in the absence or presence of flavonoids, and aggregation was recorded as described in Methods. Data were derived from four different experiments.