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. 2009 Oct 20;158(6):1579–1587. doi: 10.1111/j.1476-5381.2009.00434.x

Figure 4.

Figure 4

(A,B) Representative examples of firing rate recordings from two dorsal raphe nucleus 5-hydroxytryptamine (5-HT) neurons, which illustrate the inhibitory effect of several concentrations of 5-HT (1–200 µM) in the absence (A) and in the presence (B) of N-(2-hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide (anandamide) (10 µM). The vertical lines refer to the integrated firing rate values (spikes per 10 s), and the horizontal lines represent the time scale. Drugs were superfused at the concentration and for the time indicated by the horizontal bars. Note that anandamide did not change the inhibitory effect of 5-HT.