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DP2 receptor antagonists. Inverted 2-methyl-indole-acetic acid residues (compare with 6) are highlighted in red; ramatroban has an extra methylene (C2a). The phenylacetic acid moiety is shown in blue in fenclofenac, a lead molecule for compound 11. Compound 12, K-117 and K-604 contain a tetrahydroquinoline residue (green).
