Figure 5.
Antagonism of the inhibition by ICI118551. Cells were incubated with or without ICI118551 (30 nmol·L−1) for 45 min and then together with or without (A) indacaterol (B) formoterol or (C) isoprenaline for a further 10 min before challenge with anti-IgE (1:300) for a further 25 min. Results are expressed as the % inhibition of the control histamine releases which were for (A) 33 ± 3% and 32 ± 3% (control and ICI118551 respectively) for (B) 30 ± 4% and 33 ± 4% (control and ICI118551 respectively) and for (C) 30 ± 5% and 25 ± 4% (control and ICI118551 respectively). Values are means ± SEM, n= 12 for (A), n= 11 for (B) and n= 8 for (C).