Table 2. Organ involvement in HUVS^*.

Skin	100%	Urticarial exanthema, urticarial vasculitis, palpable purpura, angioedema
Joints	70%	Arthralgia and arthritis
Kidneys	50%	Proteinuria, hematuria, renal insufficiency, rapid progressive glomerulonephritis (RPGN)
Gastrointestinal tract	30%	Abdominal pain, nausea, vomiting, diarrhea, hepatomegaly, splenomegaly, ascites, serositis
Lungs	20%	Shortness of breath, coughing, hemoptysis, pleural effusion, chronic obstructive pulmonary disease (COPD)
Eyes	10%	Episcleritis, uveitis, conjunctivitis
Heart	Rare	Pericarditis, cardiac valve disease
Nervous system	Rare	Pseudotumor cerebri, aseptic meningitis, central or peripheral nerve palsy

^* modified from (23); HUVS, hypocomplementemic urticarial vasculitis syndrome