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. 2009 Oct 16;94(12):4728–4734. doi: 10.1210/jc.2009-0746

Table 2.

Detailed information on height status and diagnostic tests at diagnosis of IGHD II

Patient no. IGHD II Age (yr) Height at Dx Age at Dx (months) Bone age (months) Ht SDS before Rx GH Peak (ng/ml) IGF-I (ng/ml) IGFBP-3 TSH (μ U/ml) T4 (μ g/dl)
III-1 No 11 ND ND ND 0.46 ND ND ND ND ND
III-2 Yes 8 88.6 37 28 −2.02 2.2 <5 0.4 2.49 8.9
III-3 Yes 5 70.5 14.5 15 −2.46 ND <5 0.5 NA NA
III-4 Yes 2 72 16 NA −2.41 3.3 <10 0.8 1.59 8.8
III-5 Yes 1 71.2 1.04 ND −1.93 Pending 33 at 12m NA NA NA
III-6a Yes 6 75.7 27 NA −4.13 1.12/1.14 28.8 1.2 1.18 1.33
III-7 Yes 2 80 18 NA −1.87 ND 31 ND 1.66 6.2

Dx, Diagnosis; Rx, treatment; IGFBP, IGF binding protein; ND, not determined; NA, not available. 

a

MRI of III-6 showed pituitary hypoplasia.