Table 5.
IVF cycle outcomes in subjects with and without telomerase activity
| Telomerase activity present | Telomerase activity absent | |
|---|---|---|
| n | 22 | 32 |
| Median maximum pre-IVF FSH (range) | 5.7 IU/liter (3–14.3) | 7.7 IU/liter (3.5–26.1) (P = 0.04) |
| Median total amount of total gonadotropin administered (units) (range) | 2,887.5 (1,387.5–6,900) | 4031.3 (1,537.5–7,500) (P = 0.08) |
| Mean maximum estradiol | 13,157 pmol/liter ± 6,102.1 | 12,140 pmol/liter ± 5,614.4 (P = 0.55) |
| Mean follicles± sd | 24.8 ± 8.9 | 19.1 ± 10.6 (P = 0.05) |
| Median oocytes (range) | 19.5 (6–33) | 12 (2–41) (P = 0.06) |
| Mean no. of mature oocytes ± sd | 11.9 ± 5.3 | 9.3 ± 5.9 (P = 0.12) |
| Median atretic oocytes (range) | 2.4 (0–9) | 1 (0–7) (P = 0.07) |
| Mean percentage fertilization | 78% | 66% (P = 0.058) |
| Median no. of eight-cell embryos (range) | 1.5 (0–5) | 0.5 (0–6) (P = 0.1536) |
| Pregnancy rate per retrieval | 59.1% | 31.3% (P = 0.054) |
| Clinical pregnancy rate per retrieval | 50% | 28.1% (P = 0.15) |
| Miscarriage rate | 20% | 15.4% (P = 1.0) |
| Live birth rate per retrieval | 40.9% | 21.2% (P = 0.23) |