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. 2009 Oct 27;150(12):5557–5565. doi: 10.1210/en.2009-0442

Figure 1.

Figure 1

PRR mRNA and protein expression and ERK1/2 phosphorylation (p-ERK) induced by high d-glucose and in response to COX-2 inhibitor in RMCs. A, PRR expression in response to different l- or d-glucose concentrations for 14 d. B, Time course for PRR expression in response to 30 mm l- or d-glucose over 14 d. C, ERK1/2 protein phosphorylation over 14 d of 30 mm l- or d-glucose exposure. D, Effect of 12 h treatment with COX-2 inhibitor NS-398 at 10 μm on PRR expression in control and glucose-treated RMCs. Control, 30 mm l-glucose; glucose, 30 mm d-glucose. *, P < 0.01; †, P < 0.05. All the results represent the average of three independent experiments.