Table 1.

Blood insulin and glucose levels of db+ and db/db mice

	8 wk (n = 8)		16 wk (n = 4)		24 wk (n = 10)
	db+	db/db	db+	db/db	db+	db/db
Glucose (mg/dl)	163.9 ± 6.1	305.0 ± 53.3a	89.8 ± 12.4	247.3 ± 23.6b	144.4 ± 9.8	454.1 ± 53.0c
Insulin (μU/ml)	40.1 ± 9.2	516.6 ± 81.9c	22.8 ± 2.2	424.6 ± 40.5c	20.2 ± 2.6	246.3 ± 40.6c

Glucose and insulin levels are significantly higher in db/db mice compared with db+ in all age groups. We could not measure glucose and insulin levels from 2-wk animals because we were unable to collect enough blood samples for the measurement. 

^aP < 0.02; 

^bP < 0.002; 

^cP < 0.0001.