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. Author manuscript; available in PMC: 2010 Jun 15.
Published in final edited form as: J Immunol. 2009 Dec 15;183(12):7682–7691. doi: 10.4049/jimmunol.0804133

Fig. 3.

Fig. 3

Aire and chemokine expression during ontogeny of normal thymus. Thymi were collected from wild type mice at indicated embryonic (E) or postnatal (day-d, week-w, month-m) time-points and the gene expression level analyzed by qPCR. Aire expression, as well as the expression of the CCR4 and CCR7 ligands reached their peak at 10d after birth followed by a gradual decrease. The expression of the CCR9 ligand, CCL25, showed two peaks one at E13.5 and the other between 10d and 6w of age. Data are mean with S.E.M. of triplicate measurements of one out of two representative experiments.