Figure 6. PP reduces food intake via a melanocortin 4 receptor-dependent pathway.

Twenty four (24) hour food intake (g/day) in wild type (WT) and melanocortin 4 receptor knockout (MC4R ^−/−) mice after i.p. injection of increasing doses of PP or saline vehicle. Data are means ± SEM of 6–8 mice per group. * P<0.05 versus vehicle-injected wild type mice or the comparison shown by horizontal bars.