Skip to main content
. 2009 Dec 30;4(12):e8488. doi: 10.1371/journal.pone.0008488

Table 1. Number of c-Fos-like immunoreactive neurons in the brainstem and hypothalamus of wild type and Y4 receptor knockout (Y4 −/−) mice at 30 or 90 minutes after i.p. injection of saline or pancreatic polypeptide (PP).

Regions Wild type Saline (30 min) Wild type PP (30 min) Wild type PP (90 min) Y4 −/− PP (30 min)
NTS 10±2 23±6*# 14±3 8±2
AP 3±1 26±5*# 5±2 3±1
ARC 9±2 38±5*# 13±3 8±1
PVN 15±2 42±6*# 60±16* 14±3
VMHDM 20±2 71±5* 67±6* 19±3
LHA 19±4 43±8*# 78±29* 17±3

Data are means ± SEM of 4–6 mice per groups.* P<0.05 versus saline-injected wild type mice; # P<0.05 versus PP-injected wild type mice (90 minutes). NTS: nucleus tractus solitarus; AP: area postrema; ARC: arcuate nucleus of the hypothalamus; PVN: paraventricular nucleus of the hypothalamus; VMHDM: dorsomedial part of the ventromedial nucleus of the hypothalamus; LHA: lateral hypothalamic area.