Table II.

The frequency of reciprocal translocations observed in mouse spermatocytes following EO exposure

Exposure (weeks)	Concentration (p.p.m.)	Animals (n)	Reciprocal translocations (n)	Metaphases scored (n)	Reciprocal translocations (%) (mean ± SE)
6	0	6	0	775	0.000 ± 0.000
	25	7	0	668	0.000 ± 0.000
	50	7	1	670	0.150 ± 0.124
	100	6	0	810	0.000 ± 0.000
	200	3	0	334	0.000 ± 0.000
12	0	5	0	653	0.000 ± 0.000
	25	5	1	340	0.294 ± 0.252
	50	5	0	388	0.000 ± 0.000
	100	5	1	401	0.249 ± 0.245
	200	5	3	281	1.068 ± 0.302#
24	0	4	0	291	0.000 ± 0.000
	25	7	3	423	0.709 ± 0.245
	50	6	2	362	0.553 ± 0.335
	100	7	3	393	0.763 ± 0.288*
	200	4	2	284	0.704 ± 0.382
48	0	8	0	427	0.000 ± 0.000
	25	8	5	621	0.805 ± 0.248*
	50	7	3	395	0.759 ± 0.278*
	100	8	5	469	1.066 ± 0.298*
	200	7	5	443	1.129 ± 0.308*

*P < 0.05 (Fisher's exact test), ^#P < 0.05 (Cochran–Armitage test).