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. Author manuscript; available in PMC: 2009 Dec 19.
Published in final edited form as: Arch Neurol. 2009 Dec;66(12):1557–1562. doi: 10.1001/archneurol.2009.279

Figure 3.

Figure 3

Fluorescent β-pleated sheet stains label a spectrum of Aβ structures in the frontal lobe (upper panels) and CA1 subfield of hippocampus (lower panels) of postmortem brain of PiBPET-amyloid-negative participant. Amyloid is visible using 6-CN-PiB and X-34, highly fluorescent derivatives of PiB17 and Congo red18, respectively; the monoclonal antibody 6E10, targeting amino acids 1-16 (N-terminus) of Aβ identifies similar structures as denoted by the asterixes.