Table 1.

Multiple primary - standardized incidence ratios (MP-SIRs) of cancers in a high-risk Taiwan population.

Cancer Site	ICD-FT-O	Study enrollment-2005 with multiple primaries
		Males (7417 per-yrs)			Females (7734 per-yrs)			Total (15151 per-yrs)
		O**	SIR	95% CI	O**	SIR	95% CI	O**	E**	SIR	95% CI
All		52	1.2	0.91–1.6	58	1.4	1.1–1.9	110	83	1.3	1.1–1.6
All except NPC	Exclude 147	36	0.87	0.61–1.2	49	1.2	0.91–1.6	85	81	1.0	0.83–1.3
Cancers associated with infectious agents
Oral	140–149 (except 142, 147)	4	0.97	0.26–2.5	1	2.0	0.03–11	5	4.7	1.1	0.35–2.5
Salivary glands	142	1	8.3	0.11–46	0	0	0–45	1	0.2	5.0	0.07–28
Nasopharyngeal	147	16	13	7.6–22	9	21	9.6–40	25	1.6	15	10–23
Esophagus	150	1	0.70	0.01–3.9	1	6.3	0.08–35	2	1.6	1.3	0.14–4.6
Gastric	151	1	0.35	0–2.0	2	1.1	0.12–4.0	3	4.7	0.64	0.13–1.9
Liver & intrahepatic bile ducts	155	9	1.1	0.51–2.1	4	1.0	0.28–2.6	13	12	1.1	0.58–1.9
Cervix uteri	180	--	--	--	12	1.7	0.89–3.0	12	7	1.7	0.89–3.0
Vulva/vagina	184	--	--	--	1	4.0	0.05–22	1	0.25	4.0	0.05–22
Hodgkin’s lymphoma	201	0	0	0–77	1	36	0.46–198	1	0.08	13	0.17–74
Non-Hodgkin’s lymphoma	200, 202	0	0	0–3.9	1	1.2	0.03–6.8	1	1.8	0.57	0.01–3.2
Infectious + NPC		32	1.71	1.2–2.4	32	2.1	1.5–3.0	64	34	1.9	1.5–2.4
Infectious − NPC		16	0.91	0.52–1.5	23	1.6	1.0–2.4	39	32	1.2	0.87–1.7
Cancers not associated with infectious agents *
Colorectal	153–154	3	0.54	0.11–1.6	2	0.39	0.04–1.4	5	11	0.47	0.15–1.1
Respiratory system	160–165	3	0.44	0.09–1.3	4	1.1	0.29–2.8	7	11	0.66	0.27–1.4
Trachea, bronchus and lung	162	3	0.50	0.10–1.5	4	1.2	0.31–3.0	7	9.4	0.74	0.30–1.5
Breast	174–175	0	0	0–97	8	1.2	0.52–2.4	8	6.7	1.2	0.51–2.4
Urinary bladder	188–189	5	1.9	0.60–4.4	4	2.1	0.56–5.3	9	4.6	2.0	0.89–3.7

^*Restricted to individual cancers or grouped cancers with > 5 observed or expected events

^**O=observed and E=expected