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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Bioconjug Chem. 2009 Dec;20(12):2222–2230. doi: 10.1021/bc900008s

Figure 2. Reversal of platinated TFO adducts by treatment with cyanide.

Figure 2

Adducts formed by reaction of the platinated TFOs with duplex 4RY were isolated and treated with either water or 200 mM sodium cyanide. The reaction mixtures were then subjected to electrophoresis on a 20% denaturing polyacrylamide gel. The labeled strand of duplex 4RY is indicated at the top of the gel.