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. Author manuscript; available in PMC: 2010 Dec 17.
Published in final edited form as: Cell Host Microbe. 2009 Dec 17;6(6):503–512. doi: 10.1016/j.chom.2009.11.003

Figure 5. NK- cell IL-10 limits IL-12 production by DC.

Figure 5

(A) Wild type NK cells were sorted from the livers of C57BL/6 mice infected with T. gondii 7 d earlier, and cultured with IL-10-/- DCs. LPS and either anti-IL-10R or an isotype control antibody were included as indicated. Culture supernatants were harvested after 16 h and analyzed by cytometric cytokine bead array. Error bars indicate SD of triplicate cultures. (B) C57BL/6 mice received anti-NK1.1 or an isotype mAb on days -1 and 3 and were T. gondii- or sham-infected on day 0. Serum was collected on day 5 and analyzed for IL-12 by cytometric bead array. Both panels are representative of two independent experiments. *, P < 0.001