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. Author manuscript; available in PMC: 2010 Nov 25.
Published in final edited form as: Neuron. 2009 Nov 25;64(4):537–549. doi: 10.1016/j.neuron.2009.10.005

Figure 2. Disrupted whisker map in an AM251-treated rat.

Figure 2

(A) Multi-unit whisker RFs for recording sites on a penetration through the D2 column center (Pen. 01) in AM251-treated rat H08. Circle, anatomically corresponding whisker for the penetration. Blue star, measured empirical PW for each recording site. (B) Empirical PW for recording sites in all 3 center penetrations in H08. (C) Whisker receptive fields recorded along a penetration through the D2 column edge (Pen. 02), showing many mistuned sites. (D) and (E) Empirical PW in all 7 edge penetrations in H08, showing disruption of whisker map topography. Open symbols, mistuned sites. Filled symbols, correctly tuned sites. (F) P(correct tuning) for all penetrations in H08. (G) Cytochrome oxidase-stained section showing marking lesions for Pen. 01 and Pen. 02 (arrows). D2 barrel is outlined.