Table 4.
Comparisons of mtDNA D-loop MnlI RFLP pattern changes between breast cancer patients and BBD patients, between different TNM stages among breast cancer patients, and between different types of BBD patients
N | RFLP pattern changea, N (%) | OR (95% CI) | |
---|---|---|---|
Breast cancer vs BBD | |||
BBD | 59 | 9 (15.3%) | 1.00 (reference) |
Breast Cancer | 120 | 34 (28.3%) | 2.23 (0.95–5.22) |
In breast cancer patients | |||
TNM > I | 30 | 5 (16.7%) | 1.00 (reference) |
TNM = 0 & I | 90 | 29 (32.2%) | 2.40 (0.82–6.97) |
In BBD patients | |||
Proliferative | 23 | 3 (13.0%) | 1.00 (reference) |
Non-proliferative | 28 | 2 (7.1%) | 0.48 (0.07–3.37) |
The difference of MnlI RFLP patterns between tumor tissues and the corresponding adjacent non-tumor tissues.