Table 5.
Comparison of twin studies evaluating the genetic contribution to RDS.
| Number of twin pairs in study | Determination of zygosity | Genetic effect | Remarks | References |
|---|---|---|---|---|
| 31 | Based on gender, blood group, placental exam | Yes | Comparison of concordance MZ-DZ | 19 |
| 80 | Placental exam gender discordance | Yes | Comparison of concordance MZ-DZ | 20 |
| 100 | Multiple gene markers | No | Comparison of concordance MZ-DZ | 21 |
| 638 | MZ calculation | No | Comparison of concordance MZ-DZ | 10 |
| 332 | Placental exam, gender | Yes | Comparison of concordance MZ-DZ MELR and ACE model |
Present study |