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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Breast Cancer Res Treat. 2009 Apr 30;119(2):453–462. doi: 10.1007/s10549-009-0404-3

Table 3.

Multivariate analysis of SNPs genotyped in GENICA replication study

Gene Name rsID Major Allele Homozygotes
Heterozygotes
Minor Allele Homozygotes
OR (95%CI)
Per Allele
Ptrend
Cases Controls Cases Controls Cases Controls
CIT rs4766950* 271 260 499 502 232 228 1.02 (0.90-1.16) 0.79
FYN rs6914091 317 337 488 480 167 170 1.03 (0.90-1.17) 0.68
KIAA0999 rs7928320* 598 604 342 334 65 52 1.07 (0.92-1.24) 0.38
PAK6 rs16970458* 497 492 400 423 102 80 1.04 (0.90-1.19) 0.62
ROCK1 rs17202375 805 807 180 181 8 12 0.96 (0.77-1.18) 0.69
RYK rs9283588 781 789 222 212 14 11 1.07 (0.89-1.30) 0.46

NOTE: rsID: SNP identification number; OR: odds ratio; CI: confidence interval

Logistic regression analysis adjusted for age, geographical region, menopausal status, age at menarche, oral contraceptive use, age first birth, hormone replacement therapy and pack-years cigarette smoking

*

rs7928320 was significant in the general model in Mayo study (Ptrend = 0.0004)

*

rs4766950 and rs1697045 were significant in the general model in the pre-menopausal women