TABLE 2.
Multiple sequence alignment and transcription start sites (TSSs)
Entrez GeneID | Gene symbol | Sequences of ISRE or ISRE-like* | Positions of the ISRE or ISRE-like motifs (TSS: +1) | TSS† |
---|---|---|---|---|
8743 | TRAIL | tcTTTCAGTTTCCC AGTTTCCCTcctTT |
−140 to −127 −134 to −121 |
173723963 (−, chromosome 3) |
3434 | IFIT1 | AGTTTCACTTTCCC | −116 to −103 | 91142358 (+, chrosome 10) |
3437 | IFIT3 | AGTTTCACTTTCCT | −70 to −57 | 91082283 (+, chrosome 10) |
The nucleotides shown in lowercase are mismatched with the consensus ISRE motif (5′-AGTTTCNNTTTCNC/T-3′ or 5′-A/GNGAAANNGAAACT-3′).
Transcript directions in human chromosomes are shown by +/−.
ISRE indicates interferon-stimulated response element; TSS, transcription start site; TRAIL, tumor necrosis factor-related apoptosis-inducing ligand; IFIT, interferon-induced protein with tetratricopeptide repeats.