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. Author manuscript; available in PMC: 2010 Oct 1.
Published in final edited form as: J Immunother. 2009 Oct;32(8):803–816. doi: 10.1097/CJI.0b013e3181ad4092

TABLE 2.

Multiple sequence alignment and transcription start sites (TSSs)

Entrez GeneID Gene symbol Sequences of ISRE or ISRE-like* Positions of the ISRE or ISRE-like motifs (TSS: +1) TSS
8743 TRAIL tcTTTCAGTTTCCC
AGTTTCCCTcctTT
−140 to −127
−134 to −121
173723963
(−, chromosome 3)
3434 IFIT1 AGTTTCACTTTCCC −116 to −103 91142358
(+, chrosome 10)
3437 IFIT3 AGTTTCACTTTCCT −70 to −57 91082283
(+, chrosome 10)
*

The nucleotides shown in lowercase are mismatched with the consensus ISRE motif (5′-AGTTTCNNTTTCNC/T-3′ or 5′-A/GNGAAANNGAAACT-3′).

Transcript directions in human chromosomes are shown by +/−.

ISRE indicates interferon-stimulated response element; TSS, transcription start site; TRAIL, tumor necrosis factor-related apoptosis-inducing ligand; IFIT, interferon-induced protein with tetratricopeptide repeats.