Table 4.
International Germ Cell Consensus Classification for Metastatic Germ Cell Testicular Cancer10
| Prognosis | Characteristics | |
|---|---|---|
| Good |
Non-Seminoma Testis or retroperitoneal primary, and no non-pulmonary visceral metastases, and α-fetoprotein < 1,000 ng/mL, βHCG < 5,000 IU/L and LDH < 1.5 upper limit of normal −92% 5-year survival |
Seminoma Any primary site, and no non-pulmonary visceral metastases, and normal α-fetoprotein, any βHCG, any LDH −86% 5 year survival |
| Intermediate |
Non-Seminoma Testis or retroperitoneal primary, and no non-pulmonary visceral metastases, and α-fetoprotein > 1,000 ng/mL and < 10,000 ng/mL or βHCG > 5,000 IU/L and < 50,000 IU/L or LDH > 1.5 normal and< 10 normal −80% 5-year survival |
Seminoma Any primary site, and non-pulmonary visceral metastases, and normal α-fetoprotein, any βHCG, any LDH −72% 5-year survival |
| Poor |
Non-Seminoma Mediastinal primary, or non-pulmonary visceral metastases, or α-fetoprotein > 10,000 ng/mL or βHCG > 50,000 IU/L or LDH > 10 upper limit of normal −48% 5-year survival |
Seminoma None |