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. 2010 Jan 1;5(1):e8541. doi: 10.1371/journal.pone.0008541

Table 3. Individual effects of T2D polymorphisms.

SNP Locus Risk Alle. Freq. TRAIT
BMI FMI FAT WC WHR
β Se p β se p β se p β se p β se p
rs13266634 C 0.69 −0.18 0.14 0.28 −0.1 0.1 0.43 −0.09 0.23 0.76 −0.13 0.34 0.68 −1.33E-03 2.07E-03 0.59
SLC30A8
rs10811661 T 0.87 −0.04 0.18 0.87 −0.02 0.14 0.92 −0.01 0.3 0.99 0.06 0.46 0.91 2.02E-03 2.78E-03 0.54
CDKN2AB
rs7754840 C 0.33 0.15 0.13 0.35 0.08 0.1 0.5 0.17 0.22 0.52 0.2 0.33 0.61 −4.29E-04 2.00E-03 0.86
CDKAL1
rs4402960 T 0.29 0.17 0.14 0.29 0.07 0.1 0.56 −0.06 0.22 0.83 0.35 0.33 0.38 8.09E-04 2.05E-03 0.74
IGF2BP2
rs1111875 C 0.59 0.11 0.13 0.47 0.06 0.09 0.58 0.16 0.21 0.53 0.14 0.31 0.71 6.92E-04 1.91E-03 0.76
HHEX
rs1801282 C 0.9 0.25 0.22 0.31 0.22 0.16 0.24 0.65 0.35 0.13 0.38 0.52 0.53 −8.17E-05 3.17E-03 0.98
PPARG
rs5219 T 0.34 −0.04 0.13 0.81 2.1E-03 0.1 0.99 0.13 0.22 0.64 0.16 0.33 0.68 1.67E-03 1.99E-03 0.48
KCNJ11
rs7903146 T 0.28 0.1 0.14 0.56 0.08 0.1 0.5 0.28 0.23 0.33 0.39 0.34 0.34 2.32E-03 2.09E-03 0.35
TCF7L2
rs8050136 A 0.43 0.45 0.13 3.0E-03* 0.31 0.09 7.0E-03* 0.51 0.21 5.3E-02 0.79 0.32 3.0E-02* 1.02E-03 1.96E-03 0.66
FTO

All analyses are adjusted for sex and age. BMI = body mass index, FMI = fat mass index, FAT = fat %, WC = waist circumference, WHR = waist to hip ratio. b = beta coefficient, se = standard error, p = p value, * = p<0.05.