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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Curr Eye Res. 2009 Sep;34(9):737–747. doi: 10.1080/02713680903046855

Fig. 4.

Fig. 4

Effect of NAC and α-Tocopherol + Ascorbic Acid (T+AA) on genotoxic effects induced by LBP & BA8C in ARPE-19 cells. (A) ARPE-19 cells pretreated with NAC (1 mM) or T+AA (1 mM + 100 µM) for 1 or 24 h respectively and incubated with 50 µM LBP or 40 µM BA8C for 9 h and single cell gel electrophoresis was done to assess the DNA damage. The figure shows representative comet tails from each group indicative of DNA damage. (B) The bar diagram shows tail intensity (%DNA in tail) (mean ± SD) from three independent experiments. The results are given as mean ± SD. The mean in each case was calculated from three to four parallel slides, 40 comets were evaluated per slide (*P < 0.001 vs. control; **P < 0.001 vs. LBP or BA8C).