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. Author manuscript; available in PMC: 2010 Mar 1.
Published in final edited form as: Biol Blood Marrow Transplant. 2009 Mar;15(3):293–305. doi: 10.1016/j.bbmt.2008.11.034

Figure 3. Clinical Phenotype of Chimeric CLAD Dogs Following IUHCT.

Figure 3

CLAD dogs were monitored and scored using the sum of seven clinical parameters of temperature, comfort, movement, appearance, behavior, interactive behavior, and vocalization where a score ranging from 0 for normal to 4 for maximal abnormality in each category was assigned at each data point. (A). Data is represented up to 7 months of life for Duke at which point he received a postnatal BM transplant. Billie continued to not experience any CLAD clinical events up to the last time point assessed, 18 months of life (not represented on graph). The WBC counts of Billie and Duke were assessed for leukocytosis (>50,000) typical of CLAD affected dogs (B).