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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Alcohol. 2009 Dec;43(8):603–618. doi: 10.1016/j.alcohol.2009.10.006

Figure 2. Effects of flurazepam and ethanol on mIPSCs in cultured hippocampal neurons.

Figure 2

Representative tracings of voltage-clamp recordings from cultured hippocampal neurons aged 15-16 days in vitro under baseline conditions and during acute exposure to 20 μM flurazepam (A) or 50 mM ethanol (B) in the extracellular solution. A and B are shown at the same scale. Scale bars: x = 1s, y = 10 pA. Mean changes in average mIPSC amplitude (C), rise time (D), decay time constant (E), and interevent interval (F) during exposure to 20 μM flurazepam (black bars) or 50 mM ethanol (gray bars) relative to the no-drug baseline are shown. † p < 0.05, †† p < 0.01 by paired t-test. Scaled and averaged mIPSCs under baseline conditions and during exposure to flurazepam (G) or ethanol (H).