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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Alcohol. 2009 Dec;43(8):603–618. doi: 10.1016/j.alcohol.2009.10.006

Figure 6. Effect of chronic ethanol treatment on acute effects of ethanol in cultured hippocampal neurons.

Figure 6

Changes in mIPSC τd during acute application of 50 mM ethanol are shown for age-matched control neurons (gray bars) and for hippocampal neurons cultured in the presence of 50 mM ethanol for 1 or 5 days (open bars). Acute application of ethanol increased mIPSC τd in control neurons 15-16 days in vitro but not in older control neurons or ethanol treated neurons. † p < 0.05 by paired t-test comparing acute ethanol exposure to pre-drug baseline.