Table 2. Association of Kidney Function with Atrial Fibrillation in Outpatients with Stable Coronary Heart Disease.
| Variable | Tertile I (Reference) |
Tertile II OR (95% CI) |
Tertile III OR (95% CI) |
P-Value for Trend |
|---|---|---|---|---|
| eGFRCys* | ||||
| Range (ml/min/1.73m2) | > 79 | 62–79 | < 62 | |
| Unadjusted | -- | 1.59 (0.50–5.07) | 6.43 (2.45–16.87) | <0.001 |
| Age, sex, race adjusted | -- | 1.11 (0.34–3.61) | 3.72 (1.34–10.34) | 0.01 |
| Fully adjusted** | -- | 1.00 (0.29–3.45) | 3.43 (1.18–9.97) | 0.02 |
| Fully adjusted + ACR | -- | 1.21 (0.32–4.56) | 3.37 (1.02–11.14) | 0.05 |
| eGFRCr* | ||||
| Range (ml/min/1.73m2) | > 85 | 66–85 | <66 | |
| Unadjusted | -- | 1.26 (0.49–3.23) | 2.89 (1.27–6.59) | 0.01 |
| Age, sex, race adjusted | -- | 0.83 (0.21–2.20) | 1.60 (0.67–3.84) | 0.28 |
| Fully adjusted** | -- | 0.85 (0.30–2.41) | 1.69 (0.67–4.27) | 0.27 |
| Fully adjusted + ACR | -- | 1.00 (0.33–3.01) | 1.59 (0.57–4.40) | 0.37 |
| Urinary ACR* | ||||
| Range (mg/g) | <7 | 7–15 | >15 | |
| Unadjusted | -- | 2.27 (0.78–6.63) | 3.88 (1.42–10.61) | 0.01 |
| Age, sex, race adjusted | -- | 2.14 (0.72–6.34) | 4.09 (1.46–11.5) | 0.01 |
| Fully adjusted** | -- | 2.43 (0.79–7.42) | 4.89 (1.67–14.32) | 0.004 |
| Fully adjusted + eGFRcys | -- | 2.40 (0.78–7.41) | 4.36 (1.45–13.05) | 0.01 |
| Fully adjusted + eGFRCr | -- | 2.55 (0.83–7.83) | 4.61 (1.56–13.66) | 0.01 |
*
eGFRCys = estimated glomerular filtration rate based on serum cystatin C; eGFRCr = estimated glomerular filtration rate based on serum creatinine; ACR = albumin to creatinine ratio
**
Adjusted for age, age2, sex, race (white/non-white), body mass index, systolic blood pressure, diastolic blood pressure, history of hypertension, and left ventricular ejection fraction.