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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Biochem Pharmacol. 2009 Sep 24;79(3):487–497. doi: 10.1016/j.bcp.2009.08.031

Figure 3. Effects of DRE decoy oligonucleotides treatment on the on the induction of Cox-2, CYP1B1 and IGFBP-1 by TCDD.

Figure 3

Cells were transfected with 0.25 μg DRE decoy oligonucleotides or mutant DRE decoy oligonucleotides for 24 h followed by 10 nM TCDD for 2 h. The gene expression of Cox-2 (A), CYP1B1 (B) and IGFBP-1 (C) were measured. The results are expressed as relative mRNA expression levels and the statistically significant differences between control and TCDD treatment are indicated by * (p<0.05) or ** (p<0.01).