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Cmax, AUC0-t, AUC0-inf and Tmax data
| Sodium ibuprofen (n = 22) |
Ibuprofen/poloxamer (n = 22) |
Standard ibuprofen (n = 22) |
|
|---|---|---|---|
| Cmax (μg/mL) | |||
| Arithmetic mean | 43.01 | 36.06 | 32.84 |
| Geometric LS mean | 41.47 | 35.22 | 31.88 |
| AUC0-t (μg/mL/h) | |||
| Arithmetic mean | 120.57 | 124.10 | 119.10 |
| Geometric LS mean | 117.79 | 120.55 | 115.28 |
| AUC0-inf (μg/mL/h) | |||
| Arithmetic mean | 122.88 | 126.72 | 121.99 |
| Geometric LS mean | 119.73 | 122.75 | 117.71 |
| Tmax (min) | |||
| Median | 35 | 75 | 90 |
LS: least-squares
