Table 3.
Distribution of VDR genotypes and alleles between prostate cancer cases and controls
| Cases (freq) | Controls (freq) | OR(95%CI) | P value | ||
|---|---|---|---|---|---|
| FokI | FF | 33 (0.270) | 38 (0.292) | 1.00(referent) | |
| Ff | 63 (0.517) | 55 (0.423) | 1.317(0.730-2.376) | 0.361 | |
| ff | 26 (0.213) | 37 (0.285) | 0.815(0.411-1.620) | 0.560 | |
| F | 129 (0.529) | 131 (0.504) | 1.00(referent) | ||
| f | 115 (0.471) | 129 (0.496) | 0.910(0.641-1.291) | 0.597 | |
| BsmI | bb | 114 (0.934) | 108 (0.831) | 1.00(referent) | |
| Bb | 8 (0.066) | 21 (0.162) | 0.362(0.154-0.853) | 0.020 | |
| BB * | 0 (0) | 1 (0.008) | - | - | |
| b | 236 (0.964) | 237 (0.912) | 1.00(referent) | ||
| B | 8 (0.036) | 23 (0.088) | 0.351(0.154-0.800) | 0.013 | |
| Tru9I | UU | 76 (0.623) | 78 (0.600) | 1.00(referent) | |
| Uu | 41 (0.336) | 47 (0.362) | 0.902(0.533-1.525) | 0.699 | |
| uu | 5 (0.041) | 5 (0.038) | 1.039(0.289-3.742) | 0.953 | |
| U | 193 (0.791) | 203 (0.781) | 1.00(referent) | ||
| u | 51 (0.209) | 57 (0.219) | 0.947(0.618-1.452) | 0.804 | |
| ApaI | AA | 10 (0.082) | 9 (0.069) | 1.00(referent) | |
| Aa | 56 (0.459) | 61 (0.469) | 0.800(0.300-2.128) | 0.654 | |
| aa | 56 (0.459) | 60 (0.462) | 0.810(0.304-2.160) | 0.673 | |
| A | 76 (0.311) | 79 (0.304) | 1.00(referent) | ||
| a | 168 (0.689) | 181 (0.696) | 0.956(0.654-1.397) | 0.814 | |
| TaqI | TT | 112 (0.918) | 121 (0.931) | 1.00(referent) | |
| Tt | 10 (0.082) | 9 (0.069) | 1.213(0.475-3.098) | 0.687 | |
| tt | 0 (0) | 0 (0) | - | - | |
| T | 234 (0.959) | 251 (0.965) | 1.00(referent) | ||
| t | 10 (0.041) | 9 (0.035) | 1.204(0.480-3.016) | 0.693 |
*, Genotype (BB+Bb) vs bb, OR age-adjusted = 0.346, 95%CI: 0.148-0.811, P = 0.015.