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. Author manuscript; available in PMC: 2009 Dec 21.
Published in final edited form as: Eur J Immunol. 2008 Aug;38(8):2118–2130. doi: 10.1002/eji.200838213

Figure 6.

Figure 6

DNA vaccination of gag-Tg mice induces gag85-93-specific effector CTL able to protect mice from FBL-3 leukemia. (A) WT and (B) gag-Tg mice were immunized with p.DOM-gag or p.DOM DNA vaccines as indicated, on days 0 and 28; DNA booster injections at day 28 were administered, together with electroporation. Naive (unimmunized) mice served as controls. At day 36 mice were challenged by intraperitoneal injection of FBL-3 leukemia cells, and tumor development monitored. Survival data in each panel are pooled from two of two identical experiments, each giving similar results.