Table I.
Vaccine | Peptide* | Vaccine-specific responses: † | |
---|---|---|---|
wt mice | gag-Tg mice | ||
p.DOM-gag | gag85-93 | 11/11 (100%) | 12/13 (92%) |
p30 | 10/11 (91%) | 13/13 (100%) | |
p.DOM | gag85-93 | 0/7 (0%) | 0/8 (0%) |
p30 | 7/7 (100%) | 6/8 (75%) | |
Irradiated FBL-3 cells |
gag85-93 | 10/10 (100%) | 0/8 (0%) |
p30 | 0/10 (0%) | 0/8 (0%) | |
None | gag85-93 | 0/2 (0%) | 0/3 (0%) |
p30 | 0/2 (0%) | 0/3 (0%) |
Splenocytes incubated with 0.1μM gag85-93 peptide or 1μM p30 peptide.
Data presented as: number of positive responders/total mice tested (% responding).