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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Genet Epidemiol. 2010 Jan;34(1):92–99. doi: 10.1002/gepi.20439

Figure 4. Association of MAPT with Parkinson's Disease.

Figure 4

Moving average frequency of the H1H1 diplotype is plotted against age for controls (blue circles) and age at onset for patients (red triangles), each shown with 95% CPI (grey bars, light gray for at least 95% posterior probability, dark gray for at least 99% probability). The extreme low (≤30 yrs.) and high (≥80 yrs.) ages were collapsed. The MAP for patients is consistently above the MAP for controls, suggestion a uniform association that achieves highest statistical significance in the 50-70 year age spectrum (for enlarged figure, see the supplement).