Skip to main content
. Author manuscript; available in PMC: 2010 Nov 20.
Published in final edited form as: J Neurochem. 2009 Oct 14;111(6):1514–1528. doi: 10.1111/j.1471-4159.2009.06432.x

Table 3. mRNA expression difference in fold change of cytokine and neuronal markers between control and experimental animals.

Marker mRNA difference between recombinant GM-CSF-injected C57BL6 mice/control mice (PBS injected C57BL6 mice) mRNA difference between anti-GM-CSF antibody-injected C57BL6 mice/control mice (PBS injected C57BL6 mice) mRNA difference between recombinant GM-CSF plus antibody-injected C57BL6 mice/control mice (PBS injected C57BL6 mice)
TNFα 2.1 1.3 0.28
IL-1β 0.63 0.30 0.94
IL-6 0.36 0.35 2.89
Gp91 0.08 0.08 0.41
CD11b 0.29 0.13 0.91
CD11c 1.70 2.19 0.60
CD40 9.75 2.0 0.48
CD45 1.73 1.38 1.04
MHCII -2 1.22 0.81 0.66
GFAP 1.5 0.79 1.11
NeuN 0.9 1.1 0.60

Note: mRNA fold change was calculated based on comparative cycle threshold (CT) values of real-time RT-PCR between experimental mice/control mice for the following: 1). recombinant GM-CSF-injected C57BL6 mice/control mice (PBS injected C57BL6 mice), 2) anti-GM-CSF antibody-injected C57BL6 mice/control mice (PBS injected C57BL6 mice), and 3). recombinant GM-CSF plus antibody-injected C57BL6 mice/control mice (PBS injected C57BL6 mice).